Percutaneous revascularization in patients treated with thoracic radiation for cancer - 27/09/17

Doi : 10.1016/j.ahj.2017.02.014

Erin A. Fender, MD ^a,^{^{1
Both authors contributed equally to this publication.}}, Jackson J. Liang, DO ^b,^{^{1
Both authors contributed equally to this publication.}}, Terence T. Sio, MD, MS ^c, John M. Stulak, MD ^d, Ryan J. Lennon, MS ^e, Joshua P. Slusser, BS ^e, Jonathan B. Ashman, MD, PhD ^c, Robert C. Miller, MD, MS ^c, Joerg Herrmann, MD ^a, Abhiram Prasad, MD ^a, Gurpreet S. Sandhu, MD, PhD ^a,^{^⁎}
^a Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA
^b Division of Cardiovascular Disease, University of Pennsylvania, Philadelphia, PA, USA
^c Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, USA
^d Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA
^e Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA

^⁎Reprint requests: Gurpreet S. Sandhu M.D., Mayo Clinic, 200 First Street SW, Rochester, MN 55905.Mayo Clinic200 First Street SWRochesterMN55905

Abstract

Objectives

To assess coronary revascularization outcomes in patients with previous thoracic radiation therapy (XRT).

Background

Previous chest radiation has been reported to adversely affect long term survival in patients with coronary disease treated with percutaneous coronary interventions (PCI).

Methods

Retrospective, single center cohort study of patients previously treated with thoracic radiation and PCI. Patients were propensity matched against control patients without radiation undergoing revascularization during the same time period.

Results

We identified 116 patients with radiation followed by PCI (XRT-PCI group) and 408 controls. Acute procedural complications were similar between groups. There were no differences in all-cause and cardiac mortality between groups (all-cause mortality HR 1.31, P=.078; cardiac mortality 0.78, P=.49).

Conclusion

Patients with prior thoracic radiation and coronary disease treated with PCI have similar procedural complications and long term mortality when compared to control subjects.

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Abbreviations : XRT, PCI, CABG, IMA, STS, IQR

Plan

Percutaneous coronary intervention

Discussion

Limitations

Conclusions

Disclosures: None of the authors has any disclosures or relevant relationships with industry. All authors have read and approved of the final article.

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Vol 187

P. 98-103 - mai 2017 Retour au numéro

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Percutaneous revascularization in patients treated with thoracic radiation for cancer - 27/09/17

Abstract

Objectives

Background

Methods

Results

Conclusion

Plan

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