Impact of the C-reactive protein to albumin ratio on long-term outcomes after hepatic resection for colorectal liver metastases - 15/09/17
Abstract |
Background |
The aim of this study is to investigate the association C-reactive protein to albumin (CRP/Alb) ratio, a novel inflammation based prognostic score, and long-term outcomes among patients with colorectal liver metastases (CRLM) after hepatic resection.
Methods |
We retrospectively investigated 106 patients who underwent hepatic resection for CRLM and explored the relationship between CRP/Alb ratio and long-term outcomes.
Results |
In multivariate analysis, more than 4 lymph node metastases (p = 0.003), presence of neo-adjuvant chemotherapy (p = 0.008) and CRP/Alb ratio ≥ 0.04 (p = 0.021) were independent and significant predictors of cancer recurrence, while more than 4 lymph node metastases (p = 0.001), presence of neo-adjuvant chemotherapy (p < 0.001), and CRP/Alb ratio ≥ 0.04 (p = 0.002) were independent and significant predictors of poor overall survival.
Conclusions |
The CRP/Alb ratio seems to be a predictor of poor long-term outcomes in patients with CRLM after hepatic resection.
Le texte complet de cet article est disponible en PDF.Keywords : Colorectal liver metastasis, CRP, Albumin, Inflammation-based prognostic score
Plan
Vol 214 - N° 4
P. 752-756 - octobre 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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