The changing epidemiology and demography of cystic fibrosis - 01/08/17

Doi : 10.1016/j.lpm.2017.04.012

Anne L. Stephenson ^1,^3,^⁎ , Sanja Stanojevic ^2,³, Jenna Sykes ¹, Pierre-Regis Burgel ^4,⁵
¹ University of Toronto, St-Michael's hospital, Li Ka Shing knowledge institute, Keenan research centre, department of medicine, adult CF program, 30, Bond street, 6th floor, Bond Wing, M5B 1W8 Toronto, ON, Canada
² The hospital for sick children, division of respiratory medicine, Toronto, ON, Canada
³ University of Toronto, institute of health policy, management and evaluation, Toronto, ON, Canada
⁴ Sorbonne Paris Cité, université Paris Descartes, 75014 Paris, France
⁵ Assistance publique–Hôpitaux de Paris, hôpital Cochin, 75014 Paris, France

^⁎Anne L. Stephenson, University of Toronto, St-Michael's hospital, Li Ka Shing knowledge institute, Keenan research centre, department of medicine, adult CF program, 30, Bond street, 6th floor, Bond Wing, M5B 1W8 Toronto, ON, Canada.

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Summary

Once considered a pediatric disease with a poor prognosis, individuals born with cystic fibrosis (CF) today can expect to live well into adulthood. The implementation of multidisciplinary care, novel treatments and newborn screening has resulted in the rapid evolution in the demographics of the CF population. The purpose of this review is to highlight the evolving epidemiology and demographics of the CF population internationally.

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