Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation - 29/07/17

Christian Klemann, MD ^{a, b}, Sandra Ammann, PhD ^a, Miriam Heizmann, MBiol ^a, Sebastian Fuchs, PhD ^a, Sebastian F. Bode, MD ^b, Maximilian Heeg, MD ^{a, b}, Hans Fuchs, MD ^b, Kai Lehmberg, MD ^c, Udo zur Stadt, MD ^d, Claudia Roll, MD ^e, Thomas Vraetz, MD ^b, Carsten Speckmann, MD ^{a, b}, Myriam Ricarda Lorenz, PhD ^f, Klaus Schwarz, MD ^{f, g}, Jan Rohr, MD ^{a, b}, Stefan Feske, MD ^h, Stephan Ehl, MD ^{a, b}

^a Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany 

^b Center for Pediatrics, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany 

^c Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany 

^d Center for Diagnostic, University Medical Center Hamburg- Eppendorf, Hamburg, Germany 

^e Vest Children's Hospital Datteln, University Witten-Herdecke, Datteln, Germany 

^f Institute for Transfusion Medicine, University of Ulm, Ulm, Germany 

^g Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Service, Ulm, Germany 

^h Department of Pathology, New York University School of Medicine, New York, NY