Is Salt a Culprit or an Innocent Bystander in Hypertension? A Hypothesis Challenging the Ancient Paradigm - 26/07/17

Doi : 10.1016/j.amjmed.2017.03.011

James J. DiNicolantonio, PharmD ^a,^⁎ , Varshil Mehta, MBBS ^b,^c, James H. O'Keefe, MD ^a
^a Saint Luke's Mid America Heart Institute, Kansas City, Mo
^b Mount Sinai Hospital, New York, NY
^c MGM Medical College, Navi Mumbai, India

^∗Requests for reprints should be addressed to James J. DiNicolantonio, PharmD, University of Missouri–Kansas City, Cardiology, 4321 Washington St, Suite 2400, Kansas City, MO 64111.University of Missouri–Kansas City, Cardiology4321 Washington St, Suite 2400Kansas CityMO64111

Abstract

For decades the notion that an excessive consumption of salt (NaCl) leads to hypertension has persisted. However, this idea is based on opinion, not scientific proof. Despite this, every health organization, agency, and clinicians around the world have been advising salt restriction, especially to hypertensive patients. The present review article suggests that the consumption of a high-salt diet is not the cause of hypertension and that there are other factors, such as added sugars, which are causative for inducing hypertension and cardiovascular disease.

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Keywords : Diet, Hypertension, Salt, Sugar