Noncardiac chest pain after acute myocardial infarction: Frequency and association with health status outcomes - 16/05/17
Abstract |
Background |
The frequency of noncardiac chest pain (CP) hospitalization after acute myocardial infarction (AMI) is unknown, and its significance from patients' perspectives is not studied.
Objectives |
To assess the frequency of noncardiac CP admissions after AMI and its association with patients' self-reported health status.
Methods |
We identified cardiac and noncardiac CP hospitalizations in the year after AMI from the 24-center TRIUMPH registry. Hierarchical repeated-measures regression was used to identify the association of these hospitalizations with patients' self-reported health status using the Seattle Angina Questionnaire Quality of Life domain (SAQ QoL) and Short Form 12 (SF-12) physical (PCS) and mental (MCS) component summary scores.
Results |
Of 3,099 patients, 318 (10.3%) were hospitalized with CP, of whom 92 (28.9%) were hospitalized for noncardiac CP. Compared with patients not hospitalized with CP, noncardiac CP hospitalization was associated with poorer health status (SAQ QoL–adjusted differences: −8.9 points [95% CI −12.1 to −5.6]; SF-12 PCS: −2.5 points [95% CI −4.2 to −0.8] and SF-12 MCS: −3.5 points [95% CI −5.1 to −1.9]). The SAQ QoL for patients hospitalized with noncardiac CP was similar to patients hospitalized with cardiac CP (adjusted difference: 0.6 points [95% CI −3.2 to 4.5]; SF-12 PCS (0.9 points [95% CI −1.1 to 2.9]), but was worse with regard to SF-12 MCS (adjusted difference: −2.0 points [95% CI −3.9 to −0.2]).
Conclusions |
Noncardiac CP accounted for a third of CP hospitalizations within 1 year of AMI and was associated with similar disease-specific QoL as well as general physical and mental health status impairment compared with cardiac CP hospitalization.
Le texte complet de cet article est disponible en PDF.Abbreviations : CP, SAQ, SF-12 PCS, SF-12 MCS, TRIUMPH study
Plan
| Funding: Funding support was received for the TRIUMPH Registry from the National Heart, Lung, and Blood Institute (NHLBI) (P50 HL077113). Dr Qintar is supported by the NHLBI of the National Institutes of Health under Award Number T32HL110837. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Dr Chan is supported by a grant from the NHLBI (1R01HL123980). |
Vol 186
P. 1-11 - avril 2017 Retour au numéro
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