HIV-infection and psychiatric illnesses – A double edged sword that threatens the vision of a contained epidemic : The Greater Stockholm HIV Cohort Study - 18/04/17
Summary |
Context |
The Greater Stockholm HIV Cohort Study is an initiative to provide longitudinal information regarding the health of people living with HIV.
Objective |
Our aim was to explore the prevalence of HIV and its association with psychiatric co-morbidities.
Design, setting and participants |
All patients with a recorded diagnosis of HIV (any position of the ICD–10 codes B20–B24) were identified during the period 2007–2014 and related to the total population in Stockholm by January 1, 2015, N = 2.21 million. The age at diagnosis, gender, and first occurrence of an HIV diagnosis was recorded. Analyses were done by age and gender. Prevalence of psychiatric co-morbidities amongst HIV patients were recorded.
Main outcome measures |
Age-adjusted odds ratios with 95% confidence intervals were calculated with logistic regression for prevalent psychiatric co-morbidities in HIV infected individuals compared to the prevalence in the general population.
Results |
The total prevalence of HIV was 0.16%; females 0.10% (n = 1134) and males 0.21% (n = 2448). HIV-infected people were more frequently diagnosed with psychiatric illnesses and drug abuse. In females and males with HIV-diagnosis respectively, drug dependence disorder was 7.5 (7.76% vs 1.04%) and 5.1 (10.17% vs 1.98%) times higher, psychotic disorders were 6.3 (2.65% vs 0.42%) and 2.9 (1.43% vs 0.49%) times higher, bipolar disorder was 2.5 (1.41% vs 0.57%) and 3 (1.02% vs 0.34%) times higher, depression diagnosis was 1.5 (8.47% vs 5.82%) and 3.4 (10.17% vs 2.97%) higher, trauma-related disorder was 1.5 (6.00% vs 4.10%) respectively 2.9 (4.45% vs 1.56%) times higher, anxiety disorder was 1.2 (6.88% vs 5.72%) and 2.2 (6.54% vs 2.93%) times higher than in their non-infected peers.
Conclusion |
Despite effective ART, many individuals with HIV have an impaired mental health and a history of drug abuse that may threaten the vision of a contained epidemic.
Le texte complet de cet article est disponible en PDF.Keywords : Administrative databases, General population, Psychotic disorders, Bipolar disorders, Depression, Anxiety disorders, Trauma-related disorders, Drug dependence disorders, Gender, Epidemiology
Plan
Vol 74 - N° 1
P. 22-28 - janvier 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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