The Role of Human Papilloma Virus in Penile Carcinogenesis and Preneoplastic Lesions : A Potential Target for Vaccination and Treatment Strategies - 12/10/16
, Anna R. Giuliano, PhD bRésumé |
Penile cancer is a rare and devastating disease, especially at advanced stages. The etiology of penile cancer is multifactorial with multiple established risk factors including infection with the human papillomavirus (HPV). Approximately 40% of penile cancers are attributable to HPV, although the literature describing HPV as a prognostic factor is mixed. The pathogenesis of HPV infection as well as vaccination practices may provide valuable therapeutic agents to treat this rare and difficult disease.
Le texte complet de cet article est disponible en PDF.Keywords : HPV, Penile cancer, Penile –intraepithelial neoplasia (PeIN), HPV vaccination, Targeted therapy
Plan
| Disclosures: The author has nothing to disclose (G.J. Diorio); Receives research funding from Merck, Sharp & Dohme and serves as a consultant for the company related to HPV vaccines (A.R. Giuliano). |
Vol 43 - N° 4
P. 419-425 - novembre 2016 Retour au numéro
Article précédent
- Penile, Urethral, and Scrotal Cancer
- Philippe E. Spiess
- Advances in Penile-Preserving Surgical Approaches in the Management of Penile Tumors
- Tharani Mahesan, Paul K. Hegarty, Nicolas A. Watkin
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?