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Sex Differences in Cardiometabolic Risk Factors among Hispanic/Latino Youth - 25/08/16

Doi : 10.1016/j.jpeds.2016.05.037 
Carmen R. Isasi, MD, PhD 1, , Christina M. Parrinello, PhD, MPH 1, Guadalupe X. Ayala, PhD, MPH 2, Alan M. Delamater, PhD 3, Krista M. Perreira, PhD 4, Martha L. Daviglus, MD, PhD 5, John P. Elder, PhD, MPH 6, Ashley N. Marchante, MS 7, Shrikant I. Bangdiwala, PhD 8, Linda Van Horn, PhD, RD 9, Mercedes R. Carnethon, PhD 9
1 Department Epidemiology and Population Health Albert Einstein College of Medicine, Bronx, NY 
2 College of Health and Human Services, San Diego State University and the Institute for Behavioral and Community Health, San Diego, CA 
3 University of Miami Miller School of Medicine, Miami, FL 
4 Department of Public Policy, University of North Carolina at Chapel Hill, Chapel Hill, NC 
5 Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL 
6 Graduate School of Public Health and Institute for Behavioral and Community Health, San Diego State University, San Diego, CA 
7 Department of Psychology, University of Miami, Coral Gables, FL 
8 Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 
9 Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 

Reprint requests: Carmen R. Isasi, MD, PhD, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Belfer Bldg #1308D, Bronx, NY 10461.Department of Epidemiology and Population HealthAlbert Einstein College of Medicine1300 Morris Park Ave, Belfer Bldg #1308DBronxNY10461

Abstract

Objective

To determine the prevalence of obesity and cardiometabolic risk in US Hispanic/Latino youth and examine whether there are disparities by sex in cardiometabolic risk factors.

Study design

Study of Latino Youth is a population-based cross-sectional study of 1466 Hispanic/Latino youth (8-16 years old) who were recruited from 4 urban US communities (Bronx, NY, Chicago, IL, Miami, FL, and San Diego, CA) in 2012-2014. The majority of children were US-born (78%) and from low-income and immigrant families. Cardiometabolic risk factors were defined by the use of national age- and sex-specific guidelines.

Results

The prevalence of obesity was 26.5%. The prevalence of class II-III obesity, diabetes, and dyslipidemia was high (9.7%, 16.5%, and 23.3%, respectively). The prevalence of cardiometabolic risk factors increased with severity of obesity in both boys and girls. Boys had a greater prevalence of diabetes and of elevated blood pressure than girls (20.9% vs 11.8% and 8.5% vs 3.3%). In multivariable analyses, younger boys were more likely to have obesity class II-III than girls (OR 3.59; 95% CI 1.44-8.97). Boys were more likely to have prediabetes than girls (OR 2.02; 95% CI 1.35-3.02), and the association was stronger at older ages.

Conclusions

The prevalence of cardiometabolic risk factors was high in this sample of Hispanic youth. Boys had a more adverse cardiometabolic profile compared with girls that may put them at higher risk of diabetes and cardiovascular disease later in life. Reasons for this disparity and the long-term clinical implications remain to be elucidated.

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Keywords : cardiometabolic risk factors, CVD risk factors, Hispanic children, obesity, prediabetes

Abbreviations : BMI, CVD, HbA1c, HCHS, HDL-c, LDL-c, SOL


Plan


 Supported by the National Heart, Lung, and Blood Institute (NHLBI; R01HL102130). The children in the SOL are drawn from the study of adults, the Hispanic Community Health Study/Study of Latinos, which was supported by contracts from the NHLBI to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following contribute to this study through a transfer of funds to NHLBI: National Center on Minority Health and Health Disparities, the National Institute of Deafness and Other Communications Disorders, the National Institute of Dental and Craniofacial Research, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute of Neurological Disorders and Stroke, and the Office of Dietary Supplements. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders. The authors declare no conflicts of interest.


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Vol 176

P. 121 - septembre 2016 Retour au numéro
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