Comparison of one-stage vs two-stage prosthesis-based breast reconstruction: a systematic review and meta-analysis - 28/07/16
Abstract |
Background |
The aim of this review is to comprehensively compare the outcomes of one-stage and two-stage prosthesis-based breast reconstruction via meta-analytic methodology.
Data sources |
Seventeen studies comparing one-stage and two-stage prosthesis-based breast reconstruction were reviewed. The analysis divided the outcomes into 3 categories: complications, esthetic satisfaction, and total cost for completing reconstruction.
Conclusions |
The one-stage reconstruction group was at significantly higher risk for reconstruction failure and overall complications than the two-stage group. No significant difference was observed between the 2 groups in the results of nipple-sparing mastectomy. The esthetic result analysis demonstrated that both methods showed comparably positive outcomes. The one-stage group incurred lower cost for completing reconstruction than the two-stage group, despite the higher cost for treatment-related complications. Our results suggest that the risks for adverse outcome in patients undergoing one-stage reconstruction may be comparable with that of two-stage reconstruction when performed in patients receiving a nipple-sparing mastectomy. However, further well-controlled studies are required to draw more solid conclusions.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Outcomes of one-stage vs two-stage prosthetic breast reconstruction were compared. |
• | Overall, the risks of complications were higher in one-stage group than in two-stage group. |
• | For patients of nipple-sparing mastectomy, the 2 groups had comparable risks. |
• | Both groups showed esthetically pleasing outcomes. |
• | One-stage group incurred lower costs for reconstruction than the two-stage group. |
Keywords : One-stage breast reconstruction, Two-stage breast reconstruction, Prosthesis-based breast reconstruction, Implant, Tissue expander, Complication
Plan
| There were no relevant financial relationships or any sources of support in the form of grants, equipment, or drugs. |
|
| The authors declare no conflicts of interest. |
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| Ethical approval was not required. |
Vol 212 - N° 2
P. 336-344 - août 2016 Retour au numéro
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