Use of Gonadotropin-Releasing Hormone for Intractable Seizures in a Girl with Precocious Puberty without Hypothalamic Hamartoma - 24/06/16
Doi : 10.1016/j.jpeds.2016.03.078
Tuhina Govil-Dalela, MD 1, Ajay Kumar, MD, PhD, DNB 1, 2, 3, 4, Kathleen C. Moltz, MD 2, 5, Harry T. Chugani, MD 1, 2, 3, ∗⁎ 
1 Positron Emission Tomography (PET) Center, Children's Hospital of Michigan, Detroit Medical Center, Detroit, MI
2 Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI
3 Department of Neurology, Wayne State University School of Medicine, Detroit, MI
4 Department of Radiology, Wayne State University School of Medicine, Detroit, MI
5 Department of Endocrinology, Wayne State University School of Medicine, Detroit, MI
∗Reprint requests: Harry T. Chugani, MD, Division of Pediatric Neurology, Children's Hospital of Michigan, 3901 Beaubien Street, Detroit, MI 48201.Division of Pediatric NeurologyChildren's Hospital of Michigan3901 Beaubien StreetDetroitMI48201
Abstract |
The use of gonadotropin-releasing hormone analogs has been reported in the treatment of gelastic seizures and precocious puberty associated with hypothalamic hamartomas, but not in other seizure types without hypothalamic hamartoma. We describe a 7.5 year-old girl whose seizures subsided after gonadotropin-releasing hormone analog implant, administered for precocious puberty.
Le texte complet de cet article est disponible en PDF.Keywords : GnRH, seizures, estradiol
Abbreviations : CPS, GnRH, GTCS, MRI, PET
Plan
| The authors declare no conflicts of interest. |
© 2016
Elsevier Inc. Tous droits réservés.
Vol 174
P. 264-266 - juillet 2016 Retour au numéro
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