Feasibility and Safety of Transcatheter Aortic Valve Implantation Performed Without Intensive Care Unit Admission - 17/06/16
, Anais Iemmi, MD a, Benoit Lattuca, MD a, Jean-Christophe Macia, MD a, Richard Gervasoni, MD a, Francois Roubille, MD, PhD a, Thomas Gandet, MD b, Laurent Schmutz, MD c, Mariama Akodad, MD a, Audrey Agullo, MD a, Marine Verges, MD a, Erika Nogue, MD d, Gregory Marin, MD d, Nicolas Nagot, MD d, Francois Rivalland, MD e, Nicolas Durrleman, MD f, Gabriel Robert, MD g, Delphine Delseny, MD h, Bernard Albat, MD, PhD b, Guillaume Cayla, MD, PhD cAbstract |
Admission to the intensive care unit (ICU) is a standard of care after transcatheter aortic valve implantation (TAVI); however, the improvement of the procedure and the need to minimize the unnecessary use of medical resources call into question this strategy. We evaluated prospectively 177 consecutive patients who underwent TAVI. Low-risk patients, admitted to conventional cardiology units, had stable clinical state, transfemoral access, no right bundle branch block, permanent pacing with a self-expandable valve, and no complication occurring during the procedure. High-risk patients included all the others transferred to ICU. In-hospital events were the primary end point (Valve Academic Research Consortium 2 criteria). The mean age of patients was 83.5 ± 6.5 years, and the mean logistic EuroSCORE was 14.6 ± 9.7%. The balloon-expandable SAPIEN 3 valve was mainly used (n = 148; 83.6%), mostly with transfemoral access (n = 167; 94.4%). Among the 61 patients (34.5%) included in the low-risk group, only 1 (1.6%) had a minor complication (negative predictive value 98.4%, 95% confidence interval [CI] 0.91 to 0.99). Conversely, 31 patients (26.7%) from the high-risk group had clinical events (positive predictive value 26.7%, 95% CI 0.19 to 0.35), mainly conductive disorders requiring pacemaker (n = 26; 14.7%). In multivariate analysis, right bundle branch block (odds ratio [OR] 14.1, 95% CI 3.5 to 56.3), use of the self-expandable valve without a pacemaker (OR 5.5, 95% CI 2 to 16.3), vitamin K antagonist treatment (OR 3.8, 95% CI 1.1 to 12.6), and female gender (OR 2.6, 95% CI 1.003 to 6.9) were preprocedural predictive factors of adverse events. In conclusion, our results suggested that TAVI can be performed safely without ICU admission in selected patients. This strategy may optimize efficiency and cost-effectiveness of procedures.
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Vol 118 - N° 1
P. 99-106 - juillet 2016 Retour au numéro
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