Evidence-based dentistry is a concept ideally suited and applicable to special needs dentistry. As the special needs of patients varies according to the individual, so should the way we evaluate our patient, prescribe a course of treatment, and implement that treatment plan. Future generations of dental students and residents should be trained in these concepts not just for patients with special needs, but also for the general patient population. It is imperative that the dental community not retreat in the face of what many deem to be “difficult” patients with special needs. Knowledge and training can overcome many barriers to treatment.