Consequences of Sarcoidosis - 20/11/15

Doi : 10.1016/j.ccm.2015.08.013

Marjolein Drent, MD, PhD ^a,^b,^c,^⁎ , Bert Strookappe, MSc ^c,^d, Elske Hoitsma, MD, PhD ^c,^e, Jolanda De Vries, MSc, PhD ^c,^f,^g
^a Department of Pharmacology and Toxicology, Faculty of Health, Medicine and Life Science, Maastricht University, PO Box 616, Maastricht 6200 MD, The Netherlands
^b ILD Center of Excellence, St. Antonius Hospital, Koekoekslaan 1, Nieuwegein 3435 CM, The Netherlands
^c ILD Care Foundation Research Team, PO Box 18, Bennekom 6720 AA, The Netherlands
^d Department of Physical Therapy, Gelderse Vallei Hospital (ZGV), PO Box 9025, Ede 6710HN, The Netherlands
^e Department of Neurology, Alrijne Hospital, PO Box 9650, Leiden 2300 RD, The Netherlands
^f Department of Medical Psychology, St. Elisabeth Hospital Tilburg, Tilburg, The Netherlands
^g Department of Medical and Clinical Psychology, Tilburg University, PO Box 90153, Tilburg 5000 LE, The Netherlands

^∗Corresponding author. ILD Care Foundation Research Team, PO Box 18, Bennekom 6720 AA, The Netherlands.

Résumé

Sarcoidosis is a multisystem disorder of unknown cause(s). Less specific disabling symptoms, including fatigue and physical impairments, may have a major influence on the daily activities and the social and professional lives of the patients, resulting in a reduced quality of life. A multidisciplinary approach focusing on somatic and psychosocial aspects is recommended. Patients self-perceived knowledge about the importance of exercise and lifestyle should be improved. Developing the most appropriate therapeutic approach for sarcoidosis requires careful consideration of the possible impact of fatigue, small fiber neuropathy related symptoms, pain, cognitive functioning, and coping strategies. Personalized medicine and appropriate communication are beneficial.

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Keywords : Cognitive impairment, Depressive symptoms, Exercise limitation, Fatigue, Pain, Rehabilitation, Sarcoidosis, Small fiber neuropathy, Quality of life