Clinical value of relative quantification ultrasound elastography in characterizing breast tumors - 12/10/15
, Alice Carboni c, Paola Mastellari b, Sotirios Chondrogiannis b, Luca Volterrani a, b, cBienvenue sur EM-consulte, la référence des professionnels de santé.
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Abstract |
Objectives |
To evaluate ultrasound elastography (USE) using strain ratio (SR), a relative quantification approach for breast lesions characterization.
Methods |
One hundred forty-seven consecutive patients with a total of 156 breast lesions underwent USE. Technical accuracy was assessed automatically. For SR evaluation a rounded ROI was depicted inside fat (F), glandular tissue (G) and inside the lesion (L), preferably at the same depth. R1, mean value of the G and F ratio, stands for in background tissue composition elasticity. R2; mean value of L/F stands for in lesion elasticity, both evaluated in arbitrary unit (au). Two-years follow-up and pathology results were standard of reference. Mann–Whitney test, ROC analysis and Chi-square with Yates correction were used.
Results |
With the exception of 27 cysts, 17 malignant and 112 benign lesions were found. R1 values were 1.6±0.7au and 1.2±0.9au (p=0.015 NS); R2 values were 6.1±2.5au and 1.9±1.3au (p<0.001) for malignant and benign lesions, respectively. A threshold of 3.3au showed a sensitivity and specificity of 88% and 87%, respectively with an AUC of 93%. Fifteen false positive and two false negative were detected.
Conclusion |
Relative quantification of ultrasound elastography allows to find high levels of diagnostic accuracy in characterizing breast tumors above all in downgrading BI-RADS 3 and 4 lesions.
Le texte complet de cet article est disponible en PDF.Keywords : Breast neoplasm, Tissue characterization, Ultrasound, Elastography, Strain ratio
Plan
Vol 75
P. 88-92 - octobre 2015 Retour au numéro
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