Premorbid social adjustment is better in cannabis-using than non-using psychotic patients across Europe - 13/04/16
Résumé |
Introduction |
A number of authors have hypothesized that psychotic patients who consume cannabis constitute a differentiated subgroup of patients that have better cognitive and social skills, necessary to engage in illegal drug consumption, than non-using patients.
Objectives |
Given that the prevalence, and patterns, of cannabis use are culturally driven, we wanted to study first-episode psychosis (FEP) cannabis-using and non-using patients coming from different European countries as part of the EUGEI-STUDY.
Aims |
We tested the hypothesis of better premorbid social adjustment in cannabis-using FEP patients, by comparing them to FEP non cannabis users and to their respective healthy controls.
Methods |
A total of 1745 people (746 cases; 999 controls) completed the assessment for premorbid adjustment [Premorbid Adjustment Scale (PAS)] and cannabis use (CEQ-Revised). We first extracted the Premorbid Social Adjustment Factor (PSA) from PAS and then performedlinear mixed models with PSA as dependent variable and cannabis lifetime (Yes/No) and subject status (Cases/Controls) as independent variables. We then considered “Country” as random intercept.
Results |
Across all countries, PSA scores were better in patients who had smoked cannabis in their lifetime than patients who had not (P=0.009). The difference in PSA score between cannabis users and non-users was significantly greater in cases than controls (P=0.038). The relationship between PSA, cannabis lifetime (Yes/No) and subject status among nations (random intercept) is shown on Fig. 1.
Conclusions |
Cannabis-using psychotic patients show better premorbid social adjustment than non-using patients, across 5 European countries.
Le texte complet de cet article est disponible en PDF.Plan
Vol 33 - N° S
P. S102 - mars 2016 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?