Drug-induced spontaneous coronary artery dissection: Analysis of the World Health Organization's pharmacovigilance database - 22/11/24
Doi : 10.1016/j.acvd.2024.08.011
Paul Gautier a, b, c, Charles Khouri d, Michel Galinier c, Meyer Elbaz c, François Montastruc a, b, ⁎ 
a Department of Medical and Clinical Pharmacology, Centre of PharmacoVigilance and Pharmacoepidemiology, Faculty of Medicine, Toulouse University Hospital (CHU), 37, allées Jules-Guesde, 31000 Toulouse, France
b Team Pharmacologie En Population cohorteS et biobanqueS (PEPSS), centre d’investigation clinique 1436, Toulouse University Hospital (CHU), 31000 Toulouse, France
c Department of Cardiology, Institute CARDIOMET, Toulouse University Hospital (CHU), 31000 Toulouse, France
d Pharmacovigilance Department, Grenoble Alpes University Hospital, Inserm UMR 1300-HP2 Laboratory, University Grenoble Alpes, 38000 Grenoble, France
⁎Corresponding author: Department of Medical and Clinical Pharmacology, Centre of PharmacoVigilance and Pharmacoepidemiology, Faculty of Medicine, Toulouse University Hospital (CHU), 37, allées Jules-Guesde, 31000 Toulouse, France.Department of Medical and Clinical Pharmacology, Centre of PharmacoVigilance and Pharmacoepidemiology, Faculty of Medicine, Toulouse University Hospital (CHU)37, allées Jules-GuesdeToulouse31000France
Sous presse. Épreuves corrigées par l'auteur.
Disponible en ligne depuis le Friday 22 November 2024
Highlights |
• | We analysed data on spontaneous coronary artery dissection (SCAD) in VigiBase®. |
• | We identified 212 cases of SCAD in the database, with women comprising 84% of cases. |
• | Six drugs were associated with an increased risk of SCAD reporting. |
• | Six drug classes were associated with an increased risk of SCAD reporting. |
• | Our findings offer valuable insights for managing potential drug-induced SCAD. |
Plan
| ☆ | X post (Tweet): An analysis of the World Health Organization's pharmacovigilance database renews the list of drugs potentially associated with spontaneous coronary artery dissection. |
© 2024
Elsevier Masson SAS. Tous droits réservés.
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